By time when the womb did total hysterectomy of the female sex hormone replacement therapy once, the contents of the replacement therapy by the female sex hormone differ, and, for example, the case for the purpose of the treatment of menopausal disorders seems to tend to recover completely if you administer a hormone after a climacteric for approximately 1-5 years for the treatment period.
On the other hand, as for the prevention of kotsususyo and the treatment, the dosage of the long term is necessary.
When there is the womb
When you use a strong drug of the estradiol action for a long term, frequency of the endometrial cancer has to use progestin together to prevent this because many increases.
In this case (said that the onset rate of the endometrial cancer falls slightly adversely than the case that you do not use female sex hormone replacement therapy for).
That breast cancer, cerebral infarction, a vein blood clot, the onset of the myocardial infarction increase adversely is proved with the treatment when you give estrogenic + progestin replacement therapy in the study in U.S.A. for a long term.
When there is not the womb, the independent dosage of the estradiol is given by there not being possibility of the onset of the endometrial cancer, but does not usually use female sex hormone replacement therapy when you extracted the womb by endometrial cancer.
In addition, it is supposed that the onset of the breast cancer increases when you supplement estrogen for a long term and administer it.
The person whom a person with HRI (estrogenic + progesterone) did not use HRT for is more dominant, and the onset rate becomes low in the onset rate of the endometrial cancer.
You become at great risk of the endometrial cancer onset when you administer only estrogen by female sex hormone replacement therapy.
